Blar i forfatter "Marathe, Nachiket"

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    • Antibiotic sensitivity screening of Klebsiella spp. and Raoultella spp. isolated from marine bivalve molluscs reveal presence of CTX-M-producing K. pneumoniae 

      Håkonsholm, Fredrik; Hetland, Marit A.K.; Svanevik, Cecilie Smith; Sundsfjord, Arnfinn; Lunestad, Bjørn Tore; Marathe, Nachiket (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-30)
      <i>Klebsiella</i> spp. are a major cause of both nosocomial and community acquired infections, with <i>K. pneumoniae</i> being responsible for most human infections. Although <i>Klebsiella</i> spp. are present in a variety of environments, their distribution in the sea and the associated antibiotic resistance is largely unknown. In order to examine prevalence of <i>K. pneumoniae</i> and related ...

    • Structural and biochemical characterization of the environmental MBLs MYO-1, ECV-1 and SHD-1 

      Frøhlich, Christopher; Sørum, Vidar; Huber, Sandra; Samuelsen, Ørjan; Berglund, Fanny; Kristiansson, Erik; Kotsakis, Stathis D.; Marathe, Nachiket; Larsson, DG Joakim; Leiros, Hanna-Kirsti Schrøder (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-28)
      Background: MBLs form a large and heterogeneous group of bacterial enzymes conferring resistance to b-lactam antibiotics, including carbapenems. A large environmental reservoir of MBLs has been identified, which can act as a source for transfer into human pathogens. Therefore, structural investigation of environmental and clinically rare MBLs can give new insights into structure–activity relationships ...